Lawnmower Man > Sega Genesis

The intelligent Dr. Lawrence Angelo is working to increase the brain power of primates using psychotropic drugs and virtual reality training, but he goes off the rails and decides to test the techniques on his lawnmower man named Jobe, who is intellectually challenged. In the brilliant Lawnmower Man, Jobe soon runs out of control and you must battle his virtual army through the streets, blasting them all to pieces to save the world!

More epic action games that will get your juices flowing and your mind running are easily found on PRG, just check out more classics like Ring King, Gladiator and Line of Fire / Bakudan Yarou for starters!